Anant Madabhushi, the F. Alex Nason professor II of biomedical engineering and director of the Center for Computational Imaging and Personalized Diagnostics, was awarded U.S. patent 9,767,555 titled “Disease Characterization from Fused Pathology and Radiology Data.”
The described invention provides methods and apparatus associated with distinguishing invasive adenocarcinoma (IA) from in situ adenocarcinoma (AIS). The technology involves using 3-D radiological image of a region of tissue and generating an invasiveness score. The approach involves using a set of 3-D histological reconstructions combined with the set of 3-D radiological images to carefully and spatially map disease extent on to the radiologic scans.
The co-inventor is Mirabela Rusu, a former postdoctoral fellow of Madabhushi’s and currently a research scientist at GE Global Research.