SingleCare: Ryan Marino, assistant professor at the School of Medicine, explained how the use and misuse of hydroxyzine can be compared to other allergy medications. “Benadryl, or diphenhydramine, is a good comparison, as it is a similar, first-generation antihistamine with central nervous system (CNS) effects that is used for multiple indications besides just as an antihistamine, and can also be misused without being considered truly ‘addictive,’” he said.
