Work by postdoc Neekkan Dey published in Molecular Cancer Research Journal

Neekkan Dey, a postdoc in the Department of Biochemistry, wrote an article accepted for publication in Molecular Cancer Research Journal by American Association for Cancer Research (AACR).

Dey works in J. Alan Diehl’s group based at the Case Comprehensive Cancer Center.

Dey’s study, titled “miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress,” unveils the intricate interplay of PERK-responsive microRNAs (miRNAs), miR-211 and miR-217, in deciding cell fate during acute ER stress.

The study provides valuable insights into the molecular mechanisms by which PERK-induced miRNAs, particularly miR-211 and miR-217, coordinate cell fate in response to proteotoxic activation of the UPR during acute ER stress.

Read the article.