Cancer cells illustration

“Use of PET Imaging in the Assessment of Cancer Treatment and Drug Development”

The Case Comprehensive Cancer Center will host its next seminar series event Friday, Feb. 9, from noon to 1 p.m. in the Iris S. and Bert L. Wolstein Research Building auditorium.

The event will feature Anthony F. Shields, professor of oncology and medicine at Wayne State University and associate director for clinical sciences at Karmanos Cancer Institute.

Shields will present “Use of PET Imaging in the Assessment of Cancer Treatment and Drug Development.”

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Speaker Details

Anthony F. Shields is a professor of oncology at Wayne State University and works on the development of new imaging methods. He is a practicing medical oncologist specializing in gastrointestinal cancers at the Barbara Ann Karmanos Cancer Institute (KCI) in Detroit, where he is also the associate center director for clinical sciences. In this role, he oversees the conduct of clinical studies. He conducts several phase 1 clinical trials, including immunotherapy trials, and also focuses on studies for gastrointestinal tumors.

His imaging research has contributed to the development of new tracers for use with positron emission tomography (PET), such as 3’-deoxy-3’-fluorothymidine, a promising tracer for tumor proliferation, which is now used in studies around the world. Shields guides and conducts phase I-III trials, developed at KCI as part of the National Clinical Trials Network (NCTN) and with the pharmaceutical industry.

As a leader of the National Oncology PET Registry (NOPR) the use of PET was evaluated in more than 360,000 patients. He has worked on therapy and imaging using nanoparticles in both pre-clinical and clinical studies. He is active in the NCTN through SWOG and ECOG-ACRIN to promote translational studies of new imaging techniques. He has been the national co-principal investigator of the adjuvant colon cancer trial and serves on the NCI colon cancer task force.