Researchers publish article on new biosensor fabrication method

A group of Case Western Reserve University researchers published an article on single-use biosensor fabrication in Scientific Reports, titled “Advanced fabrication of biosensor on detection of Glypican-1 using S-Acetylmercaptosuccinic anhydride (SAMSA) modification of antibody.”

The team developed a new method for single-use biosensor fabrication, significantly increasing its time-efficiency and sensitivity. The developed method can be applied for other biomarkers and suitable for clinical routine use. Their research demonstrates the capability of this biosensor platform by detection of Glypican-1, a biomarker of pancreatic cancer.

The CWRU-affiliated researchers are:

  • Yifan Dai, PhD candidate in the Department of Chemical Engineering;
  • Kevin Abbasi, engineer with the Swagelok Center for Surface Analysis of Materials;
  • Samantha Butler, undergraduate research assistant in the Department of Chemical Engineering; and
  • Chung Chiun Liu, the Wallace R. Persons Professor of Sensor Technology & Control, Distinguished University Professor, professor of chemical engineering and director of the Electronics Design Center.

Read the article on the Nature website.