Pancreatic duct disruption, disconnection linked to fourfold higher risk for fistula formation Healio: Vibhu Chittajallu, fellow at the School of Medicine, discussed pancreatic duct disruption at the ACG Annual Scientific Meeting. “Acute pancreatitis is complicated by necrosis of the pancreas and peripancreatic tissues in 20% of cases,” said Chittajallu. “Necrosis of the pancreatic parenchyma may lead to loss of integrity of the pancreatic duct resulting in pancreatic duct disruption or disconnection which can be complicated by pancreatic ascites formation.” |