Professor Anant Madabhushi, team awarded patent in digital pathology, biomarker quantification

Anant MadabhushiAnant Madabhushi, director of the Center for Computational Imaging and Personalized Diagnostics and professor of biomedical engineering, was awarded U.S. patent 9,111,179, titled “High-throughput Biomarker Segmentation Utilizing Hierarchical Normalized Cuts.”

The invention relates to a novel algorithm and methodology that enables quantitative and rapid analysis of biomarkers in tissue samples. The algorithm allows for rapidly identifying all stained regions of a digitized pathology image, enabling a quantitative output of the extent of biomarker stain present in that image.

Co-inventors include Andrew Janowczyk, research associate at Case Western Reserve University, and Sharat Chandran, of the Indian Institute of Technology Bombay.

Madabhushi also is a member of the Case Comprehensive Cancer Center.