The Institute of Transformative Molecular Medicine (ITMM) at Case Western Reserve University is conducting a study on how storage affects the ability of banked blood to deliver oxygen.
We are seeking healthy adults with no known blood, lung, or circulatory disorder. Female participants will be tested to determine pregnancy status.
Participants will be asked to donate 1 unit of blood (about a pint) and then receive their blood back 21 days later (range 12-25 days) while being monitored for changes in heart rate, blood pressure and oxygen consumption.
There will be 4 study visits: 1) an initial health screen and physical exam; 2) blood donation; 3) a second health screen; and 4) blood transfusion. Visit 4 requires an overnight stay.
Study procedures involve blood sampling, placement of catheters in veins and arteries to monitor cardiovascular function and the placement of probes on the body to record oxygen delivery.